HIGHLIGHTS
- who: Diana Campos-Iglesias from the (UNIVERSITY) have published the research: USP49 deubiquitinase regulates the mitotic spindle checkpoint and prevents aneuploidy, in the Journal: (JOURNAL) of 13/01/2023
- what: The authors provide evidence regarding the crucial role of USP49 deubiquitinase in cell cycle regulation and, consequently, in cellular homeostasis maintenance. Specifically, the authors show that the depletion of USP49 in different cancer cell lines impairs proliferation. Cell Death and Disease 14:60 Thus, the authors provide evidence that USP49 is essential for spindle checkpoint activation.
- how: Flow cytometry was performed using a . . .
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