HIGHLIGHTS
- who: Chengxu Sui from the Lomonosov Moscow State University, Russia have published the research work: Uterine perivascular epithelioid tumors (PEComas) with lung metastasis showed good responses to mTOR and VEGFR inhibitors: A case report, in the Journal: (JOURNAL)
- future: The missense mutation of TSC2 (P1497H) in this case might be a potential target of mTOR inhibitors however additional preclinical studies and additional clinical evidence are needed.
SUMMARY
While the presence of aggressive PEComas is usually accompanied by locally invasive recurrences or distant metastases, a gynecologic-specific algorithm has been proposed to . . .
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