HIGHLIGHTS
- who: Yuka Asami from the DivisionShowa University have published the research work: Utility of molecular subtypes and genetic alterations for evaluating clinical outcomes in 1029 patients with endometrial cancer, in the Journal: (JOURNAL) of 16/02/2023
- what: In this study, all exons of POLE were sequenced using the Ion AmpliSeqTM Custom Panel, and the authors defined POLE-EDM as oncogenic/ pathogenic, nonsense, and in-frame deletion variants detected within the exonuclease domain of POLE that were reported as somatic hotspots .
SUMMARY
The study consisted of two independent retrospective cohorts of . . .
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