HIGHLIGHTS
- who: Woojong Lee and M. Suresh from the Boston University, United States have published the research work: Vaccine adjuvants to engage the cross-presentation pathway, in the Journal: (JOURNAL)
- future: Studies are needed to examine how the formation of lipid bodies or a low metabolic state affects different steps of ADJ-mediated DC crosspresentation such as antigen leakage from endosomes MHC-I recycling and antigen degradation. Future studies should elucidate the cellular determinants of SBA-induced LB formation and the functional role of SBA-induced lipid bodies in regulating cytosolic pathway of SBA-mediated DC . . .
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