HIGHLIGHTS
- who: Katherine Cook from the Scancell Limited, Biodiscovery Institute, University of Nottingham, Nottingham, United Kingdom, The Cancer have published the article: Vaccine Can Induce CD4-Mediated Responses to Homocitrullinated Peptides via Multiple HLA-Types and Confer Anti-Tumor Immunity, in the Journal: (JOURNAL)
- what: The authors first aimed to determine whether peptide immunization can induce homocitrulline-specific responses via HLA types other than the HLA-DP4 allele. This study has identified three homocitrullinated peptides that have different but overlapping HLA-restrictions. The authors have shown that normal human donors have a repertoire of CD4 T_cells . . .
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