Vaccine-derived polioviruses (vdpvs) [ 2 ] following pro-longed gastrointestinal replication, especially in individuals with primary immune deficiencies or in communities with low population immunity due to poor opv vaccination cov- erage, is a concern. prolonged replication is evidenced by nucleotide sequence divergence in the viral protein 1 (vp1) gene from that of the parental opv strain of > 1% for polio- virus types 1 and 3 and 0.6% for type 2 [ ]. the standard approach to poliovirus surveillance recom-

HIGHLIGHTS

• who: BRIEF REPORT and collaborators from the (UNIVERSITY) have published the article: vaccine-derived polioviruses (VDPVs) [ 2 ] following pro-longed gastrointestinal replication, especially in individuals with primary immune deficiencies or in communities with low population immunity due to poor OPV vaccination cov- erage, is a concern. Prolonged replication is evidenced by nucleotide sequence divergence in the viral protein 1 (VP1) gene from that of the parental OPV strain of > 1% for polio- virus types 1 and 3 and 0.6% for type 2 [ ]. The standard approach to poliovirus surveillance recom-, in the Journal: (JOURNAL) of 10/01 . . .
  

   

  

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