HIGHLIGHTS
- who: Isabel Acosta-Coley from the extended period and amount of data necessary to guarantee that critical factors responsible for its virulence are eliminatedThe virus is also appropriately attenuated [80]. Maintaining consistent live vaccine stocks over time is also problematic [78, ], mainly due to a loss of virus efficacy and reproductive potential. This vaccine requires cold chain distribution [82]. Another con of their development is the pressing need for , (biosafety level-3) facilities for mass production since they need to propagate high volumes/titers of the pathogen and conduct extensive testing to ensure safety [83, ]. Although LAVS . . .
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