Validation of a multiplexed and targeted lipidomics assay for accurate quantification of lipidomes

HIGHLIGHTS

  • who: Nanyan Rena Zhang from the Department of Discovery, Preclinical and Translational Medicine, and Department of Neuroscience, Merck and Co, Inc, West Point, PA, USA have published the article: Validation of a multiplexed and targeted lipidomics assay for accurate quantification of lipidomes, in the Journal: (JOURNAL)
  • what: The authors report repeatable and robust quantitation of 900 lipid species measured in NIST-SRM-1950 plasma with over 700 lipids achieving inter-assay variability below 25%. demonstrate proof of concept for biomarker discovery the authors analyzed plasma from mice treated with a glucosylceramide synthase inhibitor 1. The . . .

     

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