Validation of lipid-related therapeutic targets for coronary heart disease prevention using human genetics

HIGHLIGHTS

  • who: María Gordillo-Marañón from the Institute University College, Bangkok, Thailand have published the paper: Validation of lipid-related therapeutic targets for coronary heart disease prevention using human genetics, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • what: In parallel, the authors investigate if the genetic associations with each lipid sub-fraction and CHD are consistent with a shared causal variant using genetic co-localization. The authors discuss how this approach might be generalized to other drug_targets and clinical endpoints, providing a route to translating findings from GWAS into new drug development. The approach . . .

     

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