Validation of probabilistic genotyping software for single cell str analysis

HIGHLIGHTS

SUMMARY

    The application of single/few cell analysis to mixture deconvolution is a growing field in forensic DNA analysis. In the event of single cell analysis, high quality single source DNA profiles are often obtainable allowing for a significant decrease in the complexity of mixture analysis, since a single recovered cell originates from only one of the several individuals comprising the mixture. This improves the chances of recovering a full DNA profile if all of the collected cells originate from the same donor, or a simplified, reduced complexity mixed DNA profile (referred to as a . . .

     

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