Validation of the lc-ms/ms method for the quantification of mevalonic acid in human plasma and determination of the matrix effect

HIGHLIGHTS

  • who: G.S. Saini from the DepartmentPharmacology, Jamia Hamdard, Delhi, India have published the research work: Validation of the LC-MS/MS method for the quantification of mevalonic acid in human plasma and determination of the matrix effect, in the Journal: (JOURNAL) of 15/05/2006
  • what: In this study, a reverse-phase HPLC method with mass spectrometric detection using D7-MVA as an IS was developed.

SUMMARY

    Because the reduction of MVA levels is an indirect measure of decreased cholesterol levels, MVA can be used as a biomarker to measure . . .

     

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