HIGHLIGHTS
SUMMARY
In this research, two different alternatives to conventional extraction methods were used: pressurized liquid extraction (PLE) and ultrasound assisted extraction (USAE) techniques. PLE uses high temperatures and pressures to reduce the viscosity of solvents improving the permeability and solvent-extractive capacity to increase the performance of the extraction as yield, specificity and reproducibility but also to reduce extraction time and organic solvent consumption. An approach based on targeted metabolomics analysis using multivariate data_analysis (MVDA) was used to highlight differences among extraction conditions and evaluate the possible organic solvent reduction with the PLE technique. Ultrasound . . .
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