Variabilities in global dna methylation and β-sheet richness establish spectroscopic landscapes among subtypes of pancreatic cancer

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SUMMARY

    The interaction of the analyte with the light (electromagnetic radiation), which takes advantage of inelastic scattering, allows reading information about the composition of biologically significant molecules and functional_groups, such as phosphates, proteins, carbohydrates, phospholipids, triglycerides, and nucleic_acids. Similar to PC-1, clustering along PC-3 (Fig 6A) is related to the spectral changes in the bands from methyl and methylene motions, as much as bands of phosphate groups from nucleic_acids. By analyzing the NMF components corresponding to the nucleic_acids and proteins in cancer cells presented for each PC sample, the authors noticed that the . . .

     

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