Variable-heavy (vh) families influencing iga1&2 engagement to the antigen, fcαri and superantigen proteins g, a, and l

HIGHLIGHTS

  • who: Wei-Li Ling from the Bioinformatics Institute Newcastle University have published the Article: Variable-heavy (VH) families influencing IgA1&2 engagement to the antigen, Fcu03b1RI and superantigen proteins G, A, and L, in the Journal: Scientific Reports Scientific Reports of 29/Dec/2021

SUMMARY

    Bio‑layer interferometry (BLI) measurements of PpL and anti‑IgA immobilized Pertuzumab and Trastuzumab VH1‑7 IgA1 and 2 variants to His‑tagged Her2. To systematically study the effect of the VH framework (FWR) families on antigen binding by the IgAs, the various VH family variants were paired . . .

     

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