Variable region in streptococcal m-proteins provides stable binding with host fibrinogen for plasminogen-mediated bacterial invasion

HIGHLIGHTS

• who: Kristofor Glinton from the Plasma proteins and GAS strains hFg was obtained from ERL (South Bend, IN)GAS strains SF370, Manfredo, and , were provided by G. Lindahl (University of Lund), and JRS4, MGAS315, and , were from J. R. Scott (Emory University). M ND was obtained from M. J. Walker (University of Queensland). Strain , was purchased from the ATCC. Phylogenic analysis Phylogenic trees were constructed using the nucleotide region corresponding to the ␤-domain of SK, as described (11, ). In addition to the strains included in this study, other strains were included for statistical rigor. Cell wall extraction . . .
  

   

  

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