HIGHLIGHTS
- who: Tamar Sofer from the s Hospital University of Colorado Anschutz Medical Campus, Aurora, CO, USA have published the research: Variant-specific inflation factors for assessing population stratification at the phenotypic variance level, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
- what: In this manuscript, the authors develop variant-specific inflation factors λvs, which quantify the degree of inflation/deflation in association testing of a single genetic variant due to population stratification at the variance level. The authors develop an algorithm to compute approximate variant-specific inflation factors based on allele frequencies and variances in groups . . .
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