Variations in the hemagglutinin of the 2009 h1n1 pandemic virus: potential for strains with altered virulence phenotype?

HIGHLIGHTS

  • who: Virulence Phenotype? and collaborators from the Virginia-Maryland Regional College of Veterinary Medicine, College Park, Maryland, United States of America, Department of Veterinary Medicine, University of have published the article: Variations in the Hemagglutinin of the 2009 H1N1 Pandemic Virus: Potential for Strains with Altered Virulence Phenotype?, in the Journal: (JOURNAL) of October/14,/2010
  • what: In this report the authors show that two amino_acid mutations in the H1N1pdm HA, at positions 131 and 186, can modulate virulence for mice.
  • how: The results are consistent with this observation suggesting that the NL . . .

     

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