Varied responses to a high m.3243a>g mutation load and respiratory chain dysfunction in patient-derived cardiomyocytes

HIGHLIGHTS

• who: Sanna Ryytty and collaborators from the AIVirtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland have published the research: Varied Responses to a High m.3243A>G Mutation Load and Respiratory Chain Dysfunction in Patient-Derived Cardiomyocytes, in the Journal: Cells 2022, 2593 of /2022/
• what: The authors report here that iPSC-derived cardiomyocytes with mitochondrial mutations re- tain characteristics of tissue-specific manifestations of the patients' organs.
• how: All cytometric analysis was done with Cytoflex S Analyzer (Beckman Coulter Brea CA USA) and the data was analyzed using CytExpert . . .
  

   

  

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