HIGHLIGHTS
- who: Simone Patergnani and colleagues from the Department of Medical Sciences, Laboratory for Technologies of Advanced Therapies, University of Ferrara have published the research: Various Aspects of Calcium Signaling in the Regulation of Apoptosis, Autophagy, Cell Proliferation, and Cancer, in the Journal: (JOURNAL)
- what: To ORAI1-dependent Ca2+ influx, in this study, it was demonstrated that GA101 determines intracellular Ca2+ elevation by provoking Ca2+ release from lysosomes .
- how: The first observation was obtained by studying B-cell lymphoma-2 (BCL-2) proteins.
- future: Studies are needed to verify the effective toxicity . . .
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