HIGHLIGHTS
- What: The authors investigated the effect of ROS scavenging on myocardial oxygen delivery in female swine with DM + HFD + CKD. As endothelial nitric oxide synthase (eNOS) expression, uncoupling and phosphorylation were not altered and increased oxidative stress was documented, in this study the authors investigated the hypothesis that NO bioavailability was reduced due to ROS-mediated scavenging of NO .
- Who: R. W. A. van Drie from the Division of Experimental Cardiology, Department of Cardiology, Thoraxcenter, Erasmus University Medical Center, , CA Rotterdam, The Netherlands have published the research: Vasodilator reactive oxygen species ameliorate perturbed myocardial oxygen . . .
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