Vav2 activates c-fos serum response element and cd69 expression but negatively regulates nuclear factor of activated t cells and interleukin-2 gene activation in t lymphocyte*

HIGHLIGHTS

• who: Sophie Tartare-Deckert from the (UNIVERSITY) have published the research work: Vav2 Activates c-fos Serum Response Element and CD69 Expression but Negatively Regulates Nuclear Factor of Activated T Cells and Interleukin-2 Gene Activation in T Lymphocyte*, in the Journal: (JOURNAL) of November/22,/2000
• what: The authors compared the signaling pathways regulated by Vav1 and Vav2 following engagement of the T_cell receptor (TCR). The authors show that Vav2 is tyrosine-phosphorylated upon TCR stimulation and by co-expressed Src and Syk family kinases. The authors show that Vav2 shares with Vav1 several . . .
  

   

  

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