Ventricular tlr4 levels abrogate tlr2-mediated adverse cardiac remodeling upon pressure overload in mice

HIGHLIGHTS

• who: Elise L. Kessler and collaborators from the Department of Medical Physiology, Division of Heart and Lungs, University Medical Center Utrecht, GA Utrecht, The Netherlands have published the article: Ventricular TLR4 Levels Abrogate TLR2-Mediated Adverse Cardiac Remodeling upon Pressure Overload in Mice, in the Journal: (JOURNAL)
• what: The authors showed that ventricular TLR4 levels were high in failing murine hearts during cardiac dysfunction and, indeed, demonstrated a possible correlation of ventricular TLR2 and TLR4 during pressure overload.
• how: In the study TAC animals with TLR2 deficiency showed reduced levels of hypertrophy as . . .
  

   

  

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