Vesicular trafficking to the immune synapse: how to assemble receptor-tailored pathways from a basic building set

HIGHLIGHTS

  • who: Cosima T. Baldari from the Department of Life Sciences, University of Siena, Siena, Italy have published the research work: Vesicular Trafficking to the Immune Synapse: How to Assemble Receptor-Tailored Pathways from a Basic Building Set, in the Journal: (JOURNAL)

SUMMARY

    Adaptive immunity relies on the presentation of major histocompatibility complex-associated peptide ligand (pMHC) by an antigen-presenting cell (APC) to a cognate T_cell to allow for its activation. This process is coordinated by a highly specialized membrane domain that forms at the interface between T_cell and APC, known as the . . .

     

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