Vincristine promotes transdifferentiation of fibroblasts into myo broblasts via p38 and erk signal pathways

HIGHLIGHTS

  • who: Vincristine Promotes and collaborators from the University of Trieste, Italy have published the article: Vincristine Promotes Transdifferentiation of Fibroblasts Into Myo broblasts via P38 and ERK Signal Pathways, in the Journal: (JOURNAL)
  • what: The study shows that VCR could lead to the transformation of FBs into MBs, revealing the important role of FB proliferation in the pathogenesis of VCR-induced PF. The authors analyzed the specific protein levels of MBs. This study showed that VCR induced increased protein and gene levels of p-p38 and p-ERK, and P38 and ERK signaling pathways were . . .

     

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