HIGHLIGHTS
- who: Johannes A. Eble from the gadner Schlangenfarm (Berchtesgaden, Germany have published the research work: Vipera lebetina Venom Contains Two Disintegrins Inhibiting Laminin-binding β1 Integrins*, in the Journal: (JOURNAL) of February/21,/2003
- what: Because of its sequence homology to lebein and similar binding affinities, the authors propose the name lebein-2 for it. The authors have established and optimized their purification from the crude toxin and have characterized their integrin-inhibiting function. The study provides experimental evidence not only that lebein-1 interferes with the RGD-dependent cell attachment to fibronectin, but also . . .
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