Viral mirnas alter host cell mirna profiles and modulate innate immune responses

HIGHLIGHTS

• who: Afsar R. Naqvi and Salvador Nares from the Department of Periodontics-Mucosal Immunology Laboratory, College of Dentistry, University of Illinois at Chicago, United States have published the research work: Viral miRNAs Alter Host Cell miRNA Profiles and Modulate Innate Immune Responses, in the Journal: (JOURNAL)
• what: The authors demonstrate that disease associated HHSV miRNAs can alter cellular miRNA profiles in human oral keratinocytes (HOK), are secreted in high amounts in exosomes, and impact cell specific miRNA in Mu03c6. v-miR deregulated cellular miRs target endocytic, cytoskeletal organization related pathways and the authors validated three . . .
  

   

  

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