Virtual cocrystal screening of adefovir dipivoxyl: identification of new solid forms with improved dissolution and permeation profiles

HIGHLIGHTS

  • who: Rafael Barbas and collaborators from the Baldiri Reixac, Barcelona, Spain Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge , EW, UK have published the paper: Virtual Cocrystal Screening of Adefovir Dipivoxyl: Identification of New Solid Forms with Improved Dissolution and Permeation Profiles, in the Journal: Pharmaceutics 2022, 2310 of /2022/
  • what: New cocrystals of the antiviral drug Adefovir Dipivoxyl have been discovered by means of a combined virtual/experimental cocrystal screen, and their dissolution profiles have been further studied.
  • how: Spectral and pH data were collected with a frequency of 30 s . . .

     

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