Virus-specific secondary plasma cells produce elevated levels of high-avidity antibodies but are functionally short lived

HIGHLIGHTS

  • who: Martin F. Bachmann from the Department of Rheumatology, Immunology and Allergology, Inselspital, Bern University Hospital, University of Bern, Bern, Wellcome Building for Molecular Physiology, University of Oxford, Oxford, United Kingdom have published the paper: Virus-Specific Secondary Plasma Cells Produce Elevated Levels of High-Avidity Antibodies but Are Functionally Short Lived, in the Journal: (JOURNAL)
  • what: The authors show, that MBCs generated against Qβ proliferated during Ag recall experiments but exclusively differentiated into secondary PCs and failed to respond to multiple rounds of Ag stimulation. The aim of this study was to further characterize . . .

     

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