Visualization of conformational changes and membrane remodeling leading to genome delivery by viral class-ii fusion machinery

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  • who: Vidya Mangala Prasad from the (UNIVERSITY) have published the Article: Visualization of conformational changes and membrane remodeling leading to genome delivery by viral class-II fusion machinery, in the Journal: (JOURNAL) of 31/07/2022
  • what: This approach has enabled the authors to resolve the protein machinery and membrane deformations for similar cell entry states seen at low resolution in thin section EM of alphavirus-infected cells43,44 while capturing several previously uncharacterized intermediate states that complete the entire fusion pathway. This study provides the most detailed characterization of a class-II protein-mediated . . .

     

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