Vitamin a cycle byproducts impede dark adaptation

HIGHLIGHTS

• who: Dan Zhang from the Columbia University Medical Center, New York, New York, USA have published the paper: Vitamin A cycle byproducts impede dark adaptation, in the Journal: (JOURNAL) of January/12,/2021
• what: The authors show that later in life in the human eye these byproducts reach levels commensurate with those of vitamin A.
• how: For quantification of iso-A2E and oxo-A2E the authors used UPLC retention times and peak areas measured by a photodiode array detector at 445 ± 5 nm using the same extinction coefficient as A2E.

SUMMARY . . .

 

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