Vitamin d reverts the exosome-mediated transfer of cancer resistance to the mtor inhibitor everolimus in hepatocellular carcinoma

HIGHLIGHTS

  • who: Mariarosaria Negri from the Federal University of Rio Janeiro, Brazil have published the research: Vitamin D Reverts the Exosome-Mediated Transfer of Cancer Resistance to the mTOR Inhibitor Everolimus in Hepatocellular Carcinoma, in the Journal: (JOURNAL)
  • what: The aim of this study was to investigate whether exosomes released by human everolimus (EVE)-resistant cell lines, JHH-6 and PLC/PRF/5, were able to induce EVE resistance in JHH-6 and PLC/PRF/5 parental cells. The results of this study showed reduced phosphorylation of p70S6K in JHH-6 and PLC/PRF/5 Exo . . .

     

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