Vitamin d treatment prevents uremia-induced reductions in aortic microrna-145 attenuating osteogenic differentiation despite hyperphosphatemia

HIGHLIGHTS

• who: Natalia Carrillo-Lu00f3pez and colleagues from the (Kidney Disease), Madrid, Spain Departamento Biologu00eda Sistemas, Universidad Alcalu00e1, Alcalu00e1 Henares, Spain have published the paper: Vitamin D Treatment Prevents Uremia-Induced Reductions in Aortic microRNA-145 Attenuating Osteogenic Differentiation despite Hyperphosphatemia, in the Journal: Nutrients 2022, 2589 of /2022/
• what: Because vitamin D induces miR145 uremia and high serum P reduce it and miR-145 directly targets osterix in osteoblasts this study evaluated potential causal link between vascular miR-145 reductions and osterix-driven and its counter-regulation by vitamin D. Studies in rings from normal . . .
  

   

  

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