Voltage-gated potassium channel kv1.3 is highly expressed in human osteosarcoma and promotes osteosarcoma growth

HIGHLIGHTS

  • who: Jin Wu and colleagues from the Department of Orthopaedics, the Affiliated Southeast Hospital of Xiamen University have published the paper: Voltage-Gated Potassium Channel Kv1.3 Is Highly Expressed in Human Osteosarcoma and Promotes Osteosarcoma Growth, in the Journal: (JOURNAL)
  • what: This is the first study to show that Kv1.3 was upregulated in human osteosarcoma and downregulation of Kv1.3 suppressed osteosarcoma growth in_vivo and osteosarcoma cell proliferation in_vitro, accompanied by increased apoptosis.
  • how: In Vivo To extend the in_vitro observation on cultured MG-63 cells the authors made a xenograft . . .

     

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