Vulnerability of human cerebellar neurons to degeneration in ataxia-causing channelopathies

HIGHLIGHTS

  • who: Vikram G. Shakkottai from the Ohio State University College of Medicine, Columbus, OH, United States, Department of Neurology, University of Texas have published the article: Vulnerability of Human Cerebellar Neurons to Degeneration in Ataxia-Causing Channelopathies, in the Journal: (JOURNAL)
  • what: For the purposes of this review, the authors define neurodegeneration as is conventional for human disease; namely, either identification of frank loss of cerebellar neurons in autopsy samples or evidence of a macroscopic reduction in cerebellar volume with brain imaging, or both.

SUMMARY

    Recent advances using next-generation sequencing . . .

     

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