Vutiglabridin modulates paraoxonase 1 and ameliorates diet-induced obesity in hyperlipidemic mice

HIGHLIGHTS

• who: Dawoud Sulaiman et al. from the Department of Medicine, Division of Cardiology, David Geffen School of Medicine, University of CA Los Angeles, Los Angeles, CA, USA have published the article: Vutiglabridin Modulates Paraoxonase 1 and Ameliorates Diet-Induced Obesity in Hyperlipidemic Mice, in the Journal: Biomolecules 2023, 13, 687. of 19/01/2021
• what: The authors identify PON1 as a direct interacting protein of vutiglabridin via NPOT analysis and show that vutiglabridin increases plasma level of PON1 in both wildtype and obese/hyperlipidemic mice.
• how: The authors examined this interaction in detail . . .
  

   

  

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