Wdpcp regulates cellular proliferation and differentiation in the developing limb via hedgehog signaling

HIGHLIGHTS

  • who: Mark T. Langhans from the Department of Orthopaedic Surgery, Center for Cellular and Molecular Engineering, University of Pittsburgh School of Medicine, Technology Drive, Pittsburgh, PA, USA have published the research: Wdpcp regulates cellular proliferation and differentiation in the developing limb via hedgehog signaling, in the Journal: (JOURNAL)
  • what: The authors demonstrate a critical role for Wdpcp in modulating hedgehog signaling to facilitate multiple processes in mammalian appendicular skeletal development including proliferation, growth plate organization, and differentiation of skeletal precursors.
  • how: The authors chose to focus the studies specifically on the appendicular skeleton . . .

     

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