Wdr13 and streptozotocin-induced diabetes

HIGHLIGHTS

  • who: Arun Prakash Mishra from the (UNIVERSITY) have published the research work: Wdr13 and streptozotocin-induced diabetes, in the Journal: Nutrition and Diabetes
  • what: The authors observed a better recovery from diabetes in Wdr13-/0 mice as compared to Wdr13+/0 mice after multiple low-dose STZ administration.
  • how: Showed that Wdr13-/0 mice exhibited higher serum insulin levels better glucose clearance and significantly higher number of proliferating u03b2-cells reiterating the finding that absence of WDR13 helps in u03b2-cell hyperproliferation and recovery from diabetes further underscoring WDR13 as a key target . . .

     

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