Wdr26 functions as a scaffolding protein to promote gβγ-mediated phospholipase c β2 (plcβ2) activation in leukocytes*

HIGHLIGHTS

  • who: Zhizeng Sun from the (UNIVERSITY) have published the research work: WDR26 Functions as a Scaffolding Protein to Promote Gβγ-mediated Phospholipase C β2 (PLCβ2) Activation in Leukocytes*, in the Journal: (JOURNAL) of February/17,/2013
  • what: Similar co-immunoprecipitation experiments were carried out to determine the interaction of WDR26 with its mutants. The authors have demonstrated that the G␤␥-binding protein WDR26 serves as a scaffolding protein to promote G␤␥-mediated PLC␤2 activation by regulating PLC␤2 membrane translocation and interaction with G␤␥.
  • how: Similar results were obtained with gallein . . .

     

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