What role of the cgas-sting pathway plays in chronic pain?

HIGHLIGHTS

  • who: Xingji You from the Duke University, United States have published the Article: What role of the cGAS-STING pathway plays in chronic pain?, in the Journal: (JOURNAL)
  • future: Research may be required to provide a more comprehensive picture of STING in chronic pain and pain-related cellular signals.

SUMMARY

    Some studies indicated that STING releases proinflammatory cytokines, which may cause neuroinflammation to aggravate chronic pain (Wang et_al, 2019; Tian et_al, 2020; Sun et_al, 2021). Mitochondrial dysfunction contributes to the etiology of pain, as indicated by microscopic analysis performed on peripheral . . .

     

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