HIGHLIGHTS
- who: Christopher J. Bergin and collaborators from the Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON K H , Canada have published the article: Where to Draw the LINEu2014Are Retrotransposable Elements Here to Stay?, in the Journal: Cancers 2023, 15, 4119. of /2023/
SUMMARY
The chromatinassociated factor KDM5B has been implicated in the immune evasion of melanoma, where its depletion triggers a robust immune_response due to reduced histone-3 lysine-9 (H3K9) methylation and de-repression of endogenous TEs. Interestingly, independent studies showed that reverse_transcriptase (RT) inhibitors downregulate viral mimicry by . . .
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