Which patients are prone to suffer liver metastasis? a review of risk factors of metachronous liver metastasis of colorectal cancer

HIGHLIGHTS

• who: Mengdi Hao from the CEA, a tumor-associated antigen expressed on the surface of cancer cells originated from endoderm, is a structural protein of cell membraneIn CRC, CEA-positive rate is no less than, % [28]. CEA has been recognized as an independent prognostic factor for CRC, associated with recurrence [23, ]. Several studies identified no relationship of CEA with tumor stage and liver metastasis, due to limitations in sample size and statistical method [23, ]. Regardless of different sites of recurrence or metastasis, CEA was closely related to the liver [33, , ]. At present, CEA detection has become a . . .
  

   

  

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