HIGHLIGHTS
SUMMARY
Due to the dynamic nature of the transcriptome, gene_expression profiling has turned out to be an important research tool for elucidating disease pathophysiology and finding specific biomarkers. Preliminary studies have identified gene_expression profiles that would distinguish women with acute myocardial infarction (MI) with nonobstructive CAD from those with MI-CAD or controls, and subjects with coronary stenosis ≥50% from those with stenosis and amp;lt;50%. This study makes use of CCTA and RNA-Seq to identify whole-blood gene_expression patterns that could differentiate patients with severe coronary atherosclerotic pathology from subjects with complete . . .
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