Whole exome sequencing identifies phf14 mutations in neurocytoma and predicts responsivity to the pdgfr inhibitor sunitinib

HIGHLIGHTS

  • who: Dongyun Zhang et al. from the Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA, USA have published the research: Whole Exome Sequencing Identifies PHF14 Mutations in Neurocytoma and Predicts Responsivity to the PDGFR Inhibitor Sunitinib, in the Journal: Biomedicines 2022, 10, x FOR PEER REVIEW of /2022/
  • what: Altogether the studies demonstrate a significant mutation frequency of PHF14 in neurocytomas and preu2010 dict a favorable response to Sunitinib treatment in patients with neurocytomas harboring a PHF14 defect.a significant mutation frequency of PHF14 in neurocytomas and predict demonstrate . . .

     

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