Whole-genome sequencing facilitates patient-specific quantitative pcr-based minimal residual disease monitoring in acute lymphoblastic leukaemia, neuroblastoma and ewing sarcoma

HIGHLIGHTS

• who: Vinod Vijay Subhash from the Centre, Parkville, VIC, Australia have published the paper: Whole-genome sequencing facilitates patient-specific quantitative PCR-based minimal residual disease monitoring in acute lymphoblastic leukaemia, neuroblastoma and Ewing sarcoma, in the Journal: (JOURNAL) of 22/04/2021
• what: Whilst the primary focus of precision medicine has been the rapid identification of targetable genetic alterations , the WGS data can also be used to determine unique tumour-specific gene sequences and to develop quantitative patient-specific MRD assays, independent of tumour type, enabling DNA-based, qPCR MRD assessment for solid tumours . . .
  

   

  

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