Widespread aberrant alternative splicing despite molecular remission in chronic myeloid leukaemia patients

HIGHLIGHTS

• who: Ulf Schmitz et al. from the Computational BioMedicine Laboratory Centenary Institute, The University of Sydney, Camperdown have published the research: Widespread Aberrant Alternative Splicing despite Molecular Remission in Chronic Myeloid Leukaemia Patients, in the Journal: Cancers 2020, 12, x FOR PEER REVIEW of 11/Dec/2020
• what: The authors show that aberrant splicing in is associated with reduced expression of specific splicing factors histone modifications and reduced DNA methylation. The authors report novel transcriptional and epigenetic patterns in a multi-omics analysis of CML patient samples before and after effective front-line TKI treatment . . .
  

   

  

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