Wnt-5a: signaling and functions in health and disease

HIGHLIGHTS

  • who: Kuldeep Kumawat from the Department of Molecular Pharmacology, University of The Netherlands have published the research: WNT-5A: signaling and functions in health and disease, in the Journal: (JOURNAL)
  • what: The study showed that WNT-5A, which is also expressed in the CLL cells, promotes polarized cell migration towards chemokine gradient (CXCL10, CXCL11, CXCL12, and CCL21) in CK1-dependent manner . The study showed microglia transporting breast cancer cells into the brain tissue .
  • future: While further studies are required to elucidate a clear role of WNT-5A in CRC it is tempting to . . .

     

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