HIGHLIGHTS
- who: November and colleagues from the Syracuse University, United States have published the research: Wnt signaling directs human pluripotent stem cells into vascularized cardiac organoids with chamber-like structures, in the Journal: (JOURNAL)
- how: To test this hypothesis the authors studied the possibility of modelling chemotherapy drug-induced cardiotoxicity with cardiac organoids derived from hPSCs by treating them with supernatant medium of chemical drug Temozolomide (Temo)-treated tumor cells.
- future: To quickly screen effective and safe therapies more authentic models of human heart are needed to be developed for preclinical research (Balakumar and . . .
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