Wnt4 is heterogeneously activated in maturing β-cells to control calcium signaling, metabolism and function

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  • who: Keiichi Katsumoto from the Mice All mice were maintained in the animal facilities of either University of Copenhagen or of the Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG)Mice were housed under standardized pathogen-free conditions with free access to food and water in a, h light/dark cycle at an ambient temperature of, u00b0C and, % humidity. These genetically modified mice lines were used: Tg(Ifp1-cre/Esr1)35. Dam , (Pdx CreER), Wnt4tm Svo/tm Svo , (Wnt, fl/fl), Gt(ROSA) Sortm4(ACTB-tdTomato, EGFP)Luo , (mTmG), Gt(ROSA) Sor (Rosa, LacZ . . .

     

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