Wnt5a-vangl1/2 signaling regulates the position and direction of lung branching through the cytoskeleton and focal adhesions

HIGHLIGHTS

• who: Kuan Zhang and colleagues from the Cardiovascular Research Institute, University of California, San Francisco, California, United States of have published the research work: Wnt5a-Vangl1/2 signaling regulates the position and direction of lung branching through the cytoskeleton and focal adhesions, in the Journal: (JOURNAL)
• what: The authors investigated the function of Wnt signaling in lung branching in mice. The authors propose that mechanical force induced by noncanonical Wnt signaling mediates a coordinated alteration in the shape and orientation of a group of epithelial and mesenchymal cells. The authors focused on Vangl1gt/gt; Vangl2f . . .
  

   

  

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