Wssv exploits ampk to activate mtorc2 signaling for proliferation by enhancing aerobic glycolysis

HIGHLIGHTS

• who: Peng Zhang from the School Shandong University have published the paper: WSSV exploits AMPK to activate mTORC2 signaling for proliferation by enhancing aerobic glycolysis, in the Journal: (JOURNAL) of 13/01/2022
• what: The authors aimed to clarify the mechanism by which AMPK benefits viral proliferation. The authors investigated the role of AMPK in M. japonicus infected by WSSV and found that WSSV infection induces intracellular Ca2+ release resulting in CaMKK activation that phosphorylates AMPK and induces its partial nuclear ARTICLE Fig 8 Knockdown or activity inhibition of AMPK impaired the glycolytic pathway in . . .
  

   

  

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